The use of chiral detectors has become one of the most important application areas in HPLC. The increasing demand for chiral separation in fields such as drug analysis, drug discovery, biochemical analysis, natural product analysis, organic synthesis, etc. has resulted in a demand for better chiral stationary phases and chiral detectors.
CD-2095 Circular Dichroism Chiral Detector
Circular Dichroism based detector for chiral chromatography
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The CD-2095 is an innovative CD (Circular Dichroism) detector, using the same technology found in our steady state J series CD spectropolarimeters,
but optimized to meet HPLC requirements. The CD-2095 can simultaneously
determine both CD and UV absorption of separated peaks and give a
measurement of optical purity as well as a ratio of CD and UV to provide
a calculated g factor. Circular dichroism is an excellent tool for
measuring small molecules which have a chiral center and a chromophore.
- Simultaneous acquisition of CD, UV and g-factor signals
- Direct determination of optical isomer separation and purity
- Use for chiral directed prep chromatography
- Use with HPLC UHPLC and SFC
- Spectral scanning capability
- Up to 100× greater sensitivity than ORD
- Wide
range of applications, including drug analysis, drug discovery,
biochemical analysis, natural product analysis, organic synthesis, etc.
- Use with ChromNav and Spectra Manager for monitoring data and on the fly scanning to obtain CD maxima for accurate enantiomeric measurement.
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Click here to download the CD-2095 Circular Dichroism chiral detector leaflet.
OR-2090 Chiral Detector
Measures optical rotation for the detection of optically active compounds such as amino acids, sugars and terpenes.
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JASCO
Model OR-2090 Chiral Detector has been designed for the detection of
optically active compounds generally without a chromophore such as amino
acids, sugars, terpenes, and other compounds containing an asymmetric
carbon. In industry, these compounds are widely used as original
materials for pharmaceuticals, biochemicals, agrochemicals, cosmetics,
foods, and beverages.
- Low noise and drift
- Hg/Xe lamp to cover the wavelength range from UV to visible
- Patented flow cell for low dispersion
- Auto-aligning flow cell is easily removed for cleaning
- Artifact free
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Click here to download the OR-2090 Optical Rotation chiral detector leaflet.