The LC-2000Plus Series is JASCO's latest development in High Performance Liquid Chromatography, meeting the key requirements of today's analytical laboratory. JASCO has the largest range of optical detectors - from UV to diode array to specialist chiral detectors. The HPLC systems are coupled with the ChromNav data system to offer both HPLC and spectral data handling for most of the detectors even with the single wavelength UV detector.
Uniquely configurable, the LC-2000Plus range of high performance, low cost HPLC systems can be adapted to virtually any requirement from simple isocratic QA to advanced multi-solvent/multi-column method development and everything in between.
The LC-2000plus series is designed with a 30cm depth to maximize laboratory bench space and a safe-stacking modular architecture. The instrument has a quick set up time and is easy to use.
The LC-2000Plus HPLC series can be used as semi-micro, analytical and preparative solvent delivery systems, isocratic and high or low-pressure gradient systems as well as manual or autosampling injection systems with available temperature control. Solvent switching, mixing, degassing and a 3 column oven selection is made possible with a wide range of detectors and biocompatible chromatography.
With a choice of a PC system or direct keypad control, the LC-2000Plus series gives total solutions for system control, data acquisition, processing, interpretation and reporting. Direct control by MS software packages is enabled for high-throughput LC/MS applications.
With excellent throughput via instrument selection and optimization, this HPLC system series has a range of autosamplers to maximize laboratory time.
The LC-2000Plus HPLC systems have a low noise for maximum sensitivity and operating stability. With excellent linearity and minimum sample carry-over, the instrument has an accurate flow and is pulse-free.
The system offers validation support for regulatory requirements as well as IQ/OQ support.
From simple routine analysis to complicated system specific configurations and field upgrades, our wide range of detectors, pumps and column ovens offers the flexibility to build the ideal system.
This stand-alone system includes a pump, degasser, manual injector and UV/Vis detector. The PU-2080 Pump offers a variable flow rate and memory capacity to store up to 10 files of 64-step programs. The UV-2070/2075 UV/Vis detector provides extremely high sensitivity, spectral scanning and wavelength time-programming. The system can be easily upgraded to full automation as well as elution mode for gradient operations.
The LV-2080-03 automatic six-way valve unit enables a sequential switching of solvents during measurements such as amino acid analysis. Up to six different solvents can be connected.
The PU-2080’s integrated time programming controls a two-pump binary gradient. By using the JASCO chromatography data system, up to a 3-pump ternary gradient is possible. The MX-2080-32 is a high pressure dynamic mixer, capable of mixing up to 3 solvents under high pressure. By changing the chamber capacity, the instrument can be used in various applications from semi-micro HPLC with a volume down to 20 µL to semi-preparative HPLC.
The LG-2080-04 low-pressure gradient unit is designed to be used with the PU-2080, enabling up to a 4-solvent quaternary gradient. The PU-2089 is a compact HPLC Quaternary low pressure gradient pump designed to meet the rigorous requirements of a wide range of research and routine gradient applications. Built-in low-pressure proportioning valve and degasser enable the highest flexibility in solvent choices and excellent gradient solvent delivery.
This system enables on-line pre-treatment of samples such as deproteinization, pre-concentration, and impurity removal. The system is ideal for automated drug analysis in biosamples. The pre-treatment column selectively elutes and disposes of proteins and other macromolecules while low molecular weight compounds such as drugs are trapped (red flow line). By switching the column switching valve, the trapped compounds are introduced into a separation column and separated in low-pressure gradient mode (blue flow line). The target drug compounds eluted are detected by a UV detector or a mass spectrometer with high sensitivity and selectivity.
For more information on this system and its applications, click here.
JASCO HPLC components are fully automated and can be used as stand-alone modules using the integrated keypad and LCD display, or combined into a complete HPLC system with computer control.
ChromNAV Chromatography Data System : The total solution for HPLC system control and data management for chromatographers
Intelligent HPLC pumps offering a wide flow range for all applications
Fully automatic intelligent sample injection system for increased productivity and analytical precision.
Temperature control with excellent reproducibility and precision
Excellent optical characteristics and fully programmable
High sensitivity, high resolution and wide dynamic range
Offering over 45 years of experience in optical design and performance
Ready solutions for multiple applications
This N-methyl carbamate pesticide analysis system employs OPA post-column derivatization and fluorescence detection. High-pressure gradient elution with semi-micro HPLC and highly sensitive detection using the fluorescence detector enables a maximum 18-component analysis in one injection.
This system is designed for iminoctadine triacetate analysis. It uses a fluorescence detector to measure iminoctadine by means of ion chromatography and post-column derivatization.
This system enables high sensitivity measurements of formaldehyde and acetaldehyde at the ppb level without any pre-processing by means of post-column derivatization and fluorescence detection employing 1, 3-cyclohexanedione as a reaction reagent. This method can be applied not only to environmental water analysis, including rainwater, river water, and lake water, but also to food analysis.
Ion chromatography post-column absorption spectroscopy is employed in the analysis of cyanide ions and cyanogen chloride. This analysis method forms cyanide by allowing chloramine T to react with cyanogen eluted from the column. The cyanide then reacts with a 4-pyridinecarboxylic acid/pyrazolone solution. The blue color obtained is measured at a wavelength of 638 nm to determine the quantity of cyanide ions and cyanogen chloride
This amino acid analysis system uses post-column derivatization and fluorescence detection employing o-phthalaldehyde (OPA) as a reaction reagent. 20 kinds of protein hydrolysate amino acids were analysed in about 30 minutes. Changing the separation column and eluent makes it possible to support protein hydrolytic amino acids (Na column) or biologic amino acids (Li column).
This system analyzes polyphosphoric acid in food additives used in fish cake and dairy products such as ice cream by means of post-column derivatization and visible absorption detection. The detectable wavelength is 830 nm for the heteropoly blue complex that is generated by molybdenum and phosphorus. The system can measure tripolyphosphate from metaphosphate in a short time using an isocratic elution solution. It can also separate and detect polyphosphoric acid with a degree of polymerization of 10 or more
This is a system for simultaneously analyzing 43 different food additives at once. The diode array detector and fluorescence detector selectively detect multiple ingredients. The figure shows the chromatograms obtained at each wavelength with the photo diode array detector and the fluorescence detector. Peaks 13 (isosteviol) and 28 (diphenyl) that were not separated when using either 210 or 240 nm detection with the diode array detector were selectively detected at 270 nm (peak 13) using the diode array and fluorescence (peak 28) detectors.
For further information, click on the LC-2000Plus HPLC System applications below: