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LC-4000 Series Integrated HPLC and UHPLC Systems

The LC-4000 Series is the latest in a long history of innovative HPLC systems developed by JASCO reaching all the way back to the start of commercial HPLC in the early 1970s. The LC-4000 series HPLC provides key separation platforms at 50MPa, 70MPa and 130MPa which correspond to conventional HPLC, the increasingly popular Rapid Analysis (RHPLC) and sub 2um UHPLC, respectively.

LC-4000 Series Integrated HPLC and UHPLC Systems
 
 

HPLC System Configurations

The LC-4000 series HPLC analytical and preparative HPLC systems have a number of common features:

  • 300 mm wide footprint
  • Each system component is completely stackable into a modest height
  • The system is fully integrated with complete system monitoring
  • All user replaceable components are accessible through the front panel
  • Vertical leak/drain system to channel away solvent
  • Integrated earthquake securing option
  • All detectors include 100 Hz acquistion with interchangeable flowcells
HPLC System Configurations

Conventional HPLC and RHPLC Analytical Systems up to 70MPa

The LC-4000 Series 70 MPa system has been designed to future-proof your HPLC requirements. The LC-4000 70 MPa system can be used with conventional 3 and 5 μm particle size analytical columns at typical lower pressures around 10 to 20 MPa (1500 to 3000 psi) and can also be used with smaller particles such as shorter length UHPLC columns and superficially porous (SPP) or Coreshell that require slightly higher pressure solvent delivery to provide optimum linear velocity through the column.


RHPLC System Configurations

The LC-4000 series HPLC analytical and preparative HPLC systems have a number of common features:

  • 300 mm wide footprint
  • Each system component is completely stackable into a modest height
  • The system is fully integrated with complete system monitoring
  • All user replaceable components are accessible through the front panel
  • Vertical leak/drain system to channel away solvent
  • Integrated earthquake securing option
  • All detectors include 100 Hz acquistion with interchangeable flowcells
RHPLC System Configurations

Conventional HPLC and RHPLC Analytical Systems up to 70MPa

The LC-4000 Series 70 MPa system has been designed to future-proof your HPLC requirements. The LC-4000 70 MPa system can be used with conventional 3 and 5 μm particle size analytical columns at typical lower pressures around 10 to 20 MPa (1500 to 3000 psi) and can also be used with smaller particles such as shorter length UHPLC columns and superficially porous (SPP) or Coreshell that require slightly higher pressure solvent delivery to provide optimum linear velocity through the column.


UHPLC System Configurations

The LC-4000 series HPLC analytical and preparative HPLC systems have a number of common features:

  • 300 mm wide footprint
  • Each system component is completely stackable into a modest height
  • The system is fully integrated with complete system monitoring
  • All user replaceable components are accessible through the front panel
  • Vertical leak/drain system to channel away solvent
  • Integrated earthquake securing option
  • All detectors include 100 Hz acquistion with interchangeable flowcells
UHPLC System Configurations

UHPLC Analytical Systems at 130MPa

Ten years after the new segment of the HPLC market, UHPLC has found a niche for those that need to run a large number of samplers or get results quickly. Pioneering column technology is pushing the particle size even smaller. The near 20,000 psi operation of the LC-4000 130 MPa is designed to take advantage of the separation efficiency of the very small particles couple with longer and narrower columns. The LC-4000 130 MPa system incorporates many of the same features as the 70 MPa system, but with materials designed to withstand higher pressures.



The LC-4000 series HPLC analytical and preparative HPLC systems have a number of common features:

  • 300 mm wide footprint
  • Each system component is completely stackable into a modest height
  • The system is fully integrated with complete system monitoring
  • All user replaceable components are accessible through the front panel
  • Vertical leak/drain system to channel away solvent
  • Integrated earthquake securing option
  • All detectors include 100 Hz acquistion with interchangeable flowcells
LC-4000 series HPLC analytical and preparative HPLC systems

Preparative HPLC Systems

The LC-4000 preparative HPLC systems includes three platform options

  • Up to 20 mL/min for columns up to 21.2 mm ID
  • Up to 50 mL/min for columns up to 3 cm ID
  • Up to 120 mL/min for columns up to 5 cm ID

Large column oven for multiple preparative columns and optional automatic column switching

Open-bed fraction collector with sample trays for tubes, plates or large containers

ChromNAV-FC for fraction control using time, threshold or slope from up to 4 different signals


 

Related Instruments

Used LC

Used LC We currently have an inventory of lightly used ex-demonstration LC-4000 systems and components.

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