First discovered in 1879, supercritical fluids have been used for extraction applications since the 1950’s. The 1980’s saw an increase in their use as mobile phase for analytical separations. The work was mainly capillary scale (GC type) work, but some packed column (LC type) applications were developed. Since then, the expected growth in the technique has not taken place but the availability of new programmable pumps and an electronic back pressure regulator opens the door for future development.

Fast, Low-Cost Green Technology

Over the years, JASCO has responded to the growing emphasis on reducing chemical waste by offering an alternative to traditional HPLC with a full line of “green” SFC/SFE products. The reduction in the use of organic solvents has cost, health and safety benefits as well as faster, cleaner sample recovery during experimental procedures. The benefits of using supercritical fluids are their liquid-like densities offering higher solubility and increased column loading. They have low viscosity and are highly diffuse enabling faster separation and extraction.

Instrumentation

JASCO’s modular SFC/SFE platforms have been optimized and refined over the last 20 years to provide reliable, worry-free performance for a wide variety of applications. These applications include: analytical and preparative-scale chromatography and extraction systems used for chiral and achiral samples ranging from residual pesticide analysis to pharmaceutical drug development to petrochemical quality assurance. JASCO has also developed several dedicated platforms to help perform common analyses that are best-suited to this technology.

Analytical SFE/SFC

	Separation and sample preparation applications
	Flow rate range up to 10 mL/min
	Replaces normal phase chromatography for environmental analysis procedures
	System includes Peltier thermostatted CO2 delivery pump and pressure programmable Back Pressure Regulator
	Chiral SFC available

Preparative SFE/SFC

	Separation and purification from hundreds of milligrams to several grams with up to 30 mm I.D. columns
	Preparative scale CO2 delivery up to 120mL/min
	Fraction collection of up to 8 fractions
	Dedicated software for high throughput stack injection
	A wide range of detectors including UV-Vis, Multi-channel and CD

Support

JASCO provides 1st class service and support on all our products. We have 31 different service centers around the United States to ensure the highest level of customer satisfaction. For more information on service & support please click here...