The Model CL-2027 chemiluminescence detector is equipped with JASCO's uniquely designed coiled PTFE tube flow cell placed immediately next to a highly sensitive end-on PMT. The flow cell, combined with digital filtering allows the CL-2027 to boast the highest S/N ratio in its class. The CL-2027 satisfies the need for optimum chemiluminescence detection limits as demand increases for detection of trace amounts of lipids, nucleotides, nitrogen oxides (NOx) and catecholamines.The CL-2027 can easily be interfaced with the JASCO HPLC system using the JASCO chromatography data systems.
Advantages of chemiluminescence detection
Chemiluminescence (CL) detection does not require an excitation light beam, an essential element in fluorescence detection that produces unavoidable light scattering resulting in high background noise. The chemical excitation process enables much simpler instrumentation, greater sensitivity and wider linear dynamic range in comparison with conventional fluorescence detection. These advantages are now acquiring growing interest as a detection principle in liquid chromatography.
Ultra-trace amounts detection
The ability to measure trace amounts of compounds is one of the
inherent advantages of the chemiluminescence technique.
Advances in chemical software including the development of high
chemiluminescence efficiency reagents make femtomol (10-15
mol) level detection a reality.
Unique flow cell design
JASCO's unique design of PTFE tubing flow cell positioned
immediately in front of the high sensitivity end-on PMT detector
maximizes the signal from even small chemiluminescence
reactions. Digital filtering further enhances signal intensity and
provides highly-reliable quantitative data particularly in
applications requiring the ultimate in detection limits.
As with the other LC-2000Plus Series HPLC modules, the CL-
2027 is both simple and convenient to operate. Both sensitivity
range and gain selections are time programmable allowing the unit
to be optimized for detection of multiple peaks. The CL-2027 also
has comprehensive self diagnostics built-in to ensure maximum
productivity. Bulkhead fittings and standard analog outputs allow
the CL-2027 to be easily connected to any existing LC system.