DT-810 DISSOLUTION TESTER

System Description

The DT-810 Dissolution Tester features a unique circular design that provides uniform water temperature while utilizing a round heating element. The Direct-Center ™ automatic centering mechanism provides hands-free positioning of the dissolution vessels and drive shafts for accurate dissolution tests with high reproducibility. All components are controlled via PC using simple keystroke operations with a user friendly graphic interface.

System Features

• Meets USP, EP and JP requirements
• 21 CFR Part 11 compliant
• Excellent temperature stability using the circular bath
• Uniform temperature distribution between vessels
• Easy to set up and maintain
• Direct-center vessel centering for automatic alignment of vessels and drive shafts
• Test vessels manufactured with precise tolerances for vessel dimensions
• PC control for monitoring
• Automated tablet dropping system for dosage loading
• Automatic sampling tube positioning for the upper and lower positions
• Amber bath & vessels for light-sensitive samples

Dissolution Tester Specifications
Number of vessels	8 vessels, 1000 mL each
Spindles	Test Method: Paddle method(Standard) Rotation speed of spindle 5 to 300 rpm Accuracy of rotation speed of spindle: ± 1 %
Thermostatted Bath	Circular bath design with rotating function Stirring: Magnetic stirrer Temperature control: circular heating element Temperature range: 32-45°C (25°C room temperature) Temperature accuracy: ± 0.1°C (32-45°C) Temperature stability: ± 0.05°C (32-45°C) Temperature accuracy (dissolution vessels): ± 0.1°C (32-45°C) Safety: Overheating protection using float switch, limit controller, temperature sensor Drain port for quick and simple cleaning
Sample ports	Automated lifting and lowering by stepping motor User declared automatic sampling Sampling position: automated by method parameters and solution volume
Table dropping	Automatic (tablets, capsules, test sinker)
Vessel centering	Direct-Center™automated mechanism
Temperature sensor position	Vessel water bath, dissolution vessels (optional)
Power requirements	100,115, 200, 220, 230, 240 V; 50/60 Hz; 1100 VA (including LH-PV)
Dimensions	565(W) x 720(D) x 670(H) mm
Weight	Approx. 90 Kg (main unit including vessels and paddles; without water)
Software specifications
Functions	System control and monitoring, data collection, data analysis
Monitoring items	DT-810: bath temperature, drive shaft rotation speed, sample flow, dissolution vessel temperature (optional) Liquid handling unit: Autosampler position Fraction collector: Current sample status V-530: Absorbance value of specified cells
Liquid handling unit specifications
Model LH-PV2 LH-PV3 Number of sample lines 8 Solvent supply procedure 8-line peristaltic pump Tubing PharMed&orig; tubing Roller stepping motor, normal and reverse flow Sampling Accuracy 3% (when sampling 20 mL) Switching valve 2 valves 3 valves Dimensions 160 (W) X 352 (D) X 311(H) mm 160 (W) X 352 (D) X 395 (H) mm Weight 12 Kg 13 Kg
Fraction collector specifications
Model	FC-812AS
Sampling procedure	8-nozzle filling mechanism
Sampling system	Freely moving X, Y, Z axis positioning
Fraction collection	96 positions (20 mL test tubes)
Maximum sampling volume	20 mL
Minimum sampling interval	Sequence: 4 minutes (parameter dependent) Sampling: 1 minute for first sample, 2 minutes minimum thereafter (parameter dependent)
Contaminant free enclosure	Supplies as standard
Power requirements	100,115, 200, 220, 230, 240 V; 50/60 Hz; 50 VA
Dimensions	300 (W) X 496 (D) X 415 (H) mm
Weight	23 Kg (main unit and sample rack)
8-position flow cell specifications
Model	TQ-801
Cell(option)	8: 10 mm path length flow cells 5, 2 and 1 mm path length flow cells (optional)
Reference position	single cell holder (100 mm cuvette)